You probably just need to disable IPv6 stack in Postfix on purpose or you are getting the following messages in /var/log/mail.log file
Jul 6 00:29:18 tx120 postfix/master[3447]: warning: inet_protocols: disabling IPv6 name/address support: Address family not supported by protocol Jul 6 00:29:18 tx120 postfix/postsuper[12370]: warning: inet_protocols: disabling IPv6 name/address support: Address family not supported by protocol Jul 6 00:29:18 tx120 postfix/qmgr[12374]: warning: inet_protocols: disabling IPv6 name/address support: Address family not supported by protocol Jul 6 00:29:18 tx120 postfix/pickup[12373]: warning: inet_protocols: disabling IPv6 name/address support: Address family not supported by protocol
Actually, to disable IPv6 stack in Postfix, you just need to perform few steps
root@server:~# mcedit /etc/postfix/main.cf
change the following line in that file
inet_protocols = all
to
inet_protocols = ipv4
Restart Postfix
root@server:~# systemctl restart postfix
and check if it works well with new configuration file
root@server:~# systemctl status postfix ● postfix.service - Postfix Mail Transport Agent Loaded: loaded (/lib/systemd/system/postfix.service; enabled; vendor preset: enabled) Active: active (exited) since Fri 2018-07-06 01:04:46 CEST; 12s ago Process: 5447 ExecReload=/bin/true (code=exited, status=0/SUCCESS) Process: 12768 ExecStart=/bin/true (code=exited, status=0/SUCCESS) Main PID: 12768 (code=exited, status=0/SUCCESS) Jul 06 01:04:46 tx120 systemd[1]: Starting Postfix Mail Transport Agent... Jul 06 01:04:46 tx120 systemd[1]: Started Postfix Mail Transport Agent.
PS
Postfix is well known replacement for sendmail
Disclaimer
Image of the article is taken from the Postfix project website http://www.postfix.org